topic

Calcium-phosphate biomineralization

칼슘-인산염 생광물화

Ca₃P₁ 전핵형성 클러스터가 DCPD, 하이드록시아파타이트(HAP), β-TCP, Mg-안정화 휘틀록석(WH)과 같은 결정질 상보다 선행하는 비고전적 2단계 경로를 통한 칼슘-인산염 생광물의 형성으로, 상 선택은 pH, 과잉 Mg, 그리고 핵형성을 주형화하거나 억제하고 조골세포 반응을 조절하는 산성 유기 첨가제(pAsp, 황산화 콘드로이틴)에 의해 조율된다.

구성 페이지 (12)

묶인 페이지 (12)

Calcium-phosphate prenucleation cluster (Ca₃P₁)Calcium-phosphate prenucleation pathway (non-classical two-stage)CaP prenucleation-cluster Ca/P ratio (time-resolved, TOF-MEIS)Dicalcium phosphate dihydrate (DCPD, CaHPO4·2H2O)Hydroxyapatite (HAP, Ca10(PO4)6(OH)2)Whitlockite nanocrystal (WH, Ca18Mg2(HPO4)2(PO4)12)Tricalcium phosphate (beta-TCP, Ca3(PO4)2)pH-driven HAP→WH calcium phosphate phase transformation Excess-Mg + acidic-pH dual-lever whitlockite synthesis Osteoblast proliferation & bone-gene expression (WH vs HAP vs TCP)Poly(aspartic acid) (pAsp) — nucleation inhibitor Sulfate-group sequential ion recruitment (CS-driven HAP nucleation)

로컬 그래프 (12 연결)

드래그·휠로 탐색 · 노드 호버 → 관계 · 클릭 → 페이지

나가는 연결 (0)

없음

역링크 (12)

← part_of

Calcium-phosphate prenucleation cluster (Ca₃P₁)

member of umbrella calcium-phosphate-biomineralization

← part_of

Calcium-phosphate prenucleation pathway (non-classical two-stage)

member of umbrella calcium-phosphate-biomineralization

← part_of

CaP prenucleation-cluster Ca/P ratio (time-resolved, TOF-MEIS)

member of umbrella calcium-phosphate-biomineralization

← part_of

Dicalcium phosphate dihydrate (DCPD, CaHPO4·2H2O)

member of umbrella calcium-phosphate-biomineralization

← part_of

Hydroxyapatite (HAP, Ca10(PO4)6(OH)2)

member of umbrella calcium-phosphate-biomineralization

← part_of

Whitlockite nanocrystal (WH, Ca18Mg2(HPO4)2(PO4)12)

member of umbrella calcium-phosphate-biomineralization

← part_of

Tricalcium phosphate (beta-TCP, Ca3(PO4)2)

member of umbrella calcium-phosphate-biomineralization

← part_of

pH-driven HAP→WH calcium phosphate phase transformation

member of umbrella calcium-phosphate-biomineralization

← part_of

Excess-Mg + acidic-pH dual-lever whitlockite synthesis

member of umbrella calcium-phosphate-biomineralization

← part_of

Osteoblast proliferation & bone-gene expression (WH vs HAP vs TCP)

member of umbrella calcium-phosphate-biomineralization

← part_of

Poly(aspartic acid) (pAsp) — nucleation inhibitor

member of umbrella calcium-phosphate-biomineralization

← part_of

Sulfate-group sequential ion recruitment (CS-driven HAP nucleation)

member of umbrella calcium-phosphate-biomineralization